منابع مشابه
High strain mechanical loading rapidly induces tendon apoptosis: an ex vivo rat tibialis anterior model.
BACKGROUND The role of apoptosis, or programmed cell death, has only recently been explored in tendon. OBJECTIVE To investigate the development of apoptosis after high strain loading of rat tendon. METHODS The right tibialis anterior tendons of three rats were prepared for mechanical loading, and left tendons were prepared identically as non-loaded controls. Tendon was loaded with 20% strai...
متن کاملIn vivo investigation of tendon responses to mechanical loading.
Tendons transmit skeletal muscle forces to bone and are essential in all voluntary movement. In turn, movement appears to affect tendon properties, and in recent years considerable effort has been put into discovering how tendon tissue responds to mechanical stimuli in vivo. Months and years of mechanical loading can influence the gross morphology of tendon, seen as an increase tendon cross sec...
متن کاملTendon fatigue in response to mechanical loading.
Tendinopathies are commonly attributable to accumulation of sub-rupture fatigue damage from repetitive use. Data is limited to late stage disease from patients undergoing surgery, motivating development of animal models, such as ones utilizing treadmill running or repetitive reaching, to investigate the progression of tendinopathies. We developed an in vivo model using the rat patellar tendon t...
متن کاملEvaluating changes in tendon crimp with fatigue loading as an ex vivo structural assessment of tendon damage.
The complex structure of tendons relates to their mechanical properties. Previous research has associated the waviness of collagen fibers (crimp) during quasi-static tensile loading to tensile mechanical properties, but less is known about the role of fatigue loading on crimp properties. In this study (IACUC approved), mouse patellar tendons were fatigue loaded while an integrated plane polaris...
متن کاملTendon Healing: Mechanical Loading, Microdamage and Gene Expression
...................................................................................................................................................... 1 POPULÄRVETENSKAPLIG SAMMANFATTNING ............................................................................ 2 LIST OF PAPERS ......................................................................................................................
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2007
ISSN: 1940-087X
DOI: 10.3791/209